When images are converted for TN generation the ICC profile isn't stripped and can cause issues. This might be the case for other CModels as well but I've only tested Large image this far.
Issue is only viewable on Firefox.
Example of a working profile
icc:description: sRGB IEC61966-2.1
icc:manufacturer: IEC http://www.iec.ch
icc:model: IEC 61966-2.1 Default RGB colour space - sRGB
Example of a profile that causes irregularity with some browsers
icc:description: SF_R (UMAX PowerLook 2100XL)
Forgot to add:
We have this issue live on our site: http://digital.lib.utk.edu/collections/islandora/object/arrowmont%3Aarrsimple?page=6